[šŸ‡§šŸ‡©] - Pharmaceutical Industry in Bangladesh | Page 2 | World Defense Forum

World Military Forum

Delivering Global Defense & Political Insights to You

The Hub Defense of All Nations

[šŸ‡§šŸ‡©] Pharmaceutical Industry in Bangladesh

  • Thread starter Thread starter Saif
  • Start date Start date
  • Replies Replies 20
  • Views Views 1K
G Bangladesh Defense Forum

Local pharma lights up hope in cancer treatment

1720827680462.png

Photo: Anisur Rahman

The pharmaceutical sector of Bangladesh has achieved many milestones over the past 14 years. Not only do local companies now meet 90 percent of the country's demand for medicines, but the products are also exported to around 150 countries, fetching hundreds of millions of dollars.

However, among the most significant strides the sector has made is its advancement in the manufacture of life-saving cancer medication.

In the last 14 years, pharmaceutical companies like Beacon, Eskayef, Renata, Incepta, Healthcare, and Techno Pharma produced more than 110 varieties of oncological drugs.

Around 17 local companies are manufacturing anti-cancer drug products. Thanks to their bold initiatives, patients in Bangladesh can now access cancer drugs at affordable prices, which have brought down the cost of treatment.

Monjural Alam, chief executive officer of Beacon Medicare, said the prices of such drugs in Europe and the US are beyond the purchasing capacity of many patients.

1720827718064.png


"There is a scarcity of life-saving drugs worldwide. When the drugs are available, they are usually beyond the reach of common people. To this end, we have established a facility within our company to serve global patients," he said.

Before 2009, there was scepticism regarding Beacon's ability to manufacture sophisticated cancer drugs. However, the plant has become successful, and patients can buy life-saving drugs at reasonable prices.

Claiming that Beacon pioneered the manufacturing of cancer drugs in Bangladesh, he said it now meets around half of the local demand for cancer drugs.

Before 2010, Bangladesh relied entirely on imports for oncology drugs. This means only patients from financially solvent families could afford cancer treatment due to the exorbitant cost of medicines. Today, it not only meets domestic consumption but also serves as an exporter in the global market.

"This achievement was made possible by the dedication of local pharmaceutical companies and the trust placed by doctors and patients in local products," Alam said.

According to manufacturers, local companies produce around 99 percent of oncology drugs, yet some patients still resort to imported drugs or unofficial imports.

1720827750909.png


Recently, pharmaceutical companies have been affected immensely due to the supply chain disruptions and the dollar crisis against the backdrop of the Russia-Ukraine war. The situation is improving following the collaborative efforts of the government and drug manufacturers.

It provides medicines worth Tk 3 crore to poor patients annually.

Beacon plans to establish a second oncology plant to meet the increasing global demand for cancer drugs. The company is also considering setting up a palliative care centre to alleviate the suffering of patients.

A relative newcomer to the scene is Eskayef Oncology, which commenced its journey in 2018. However, the company, which boasts advanced technologies, has expanded its footprint beyond Bangladesh in no time.

It is one of the few Asian companies to have secured approval from the European Union Good Manufacturing Practice (EU GMP) to produce anti-cancer medicines. This is recognised by 27 nations of the EU and is considered a passport for entry into the global market.

"This recognition facilitated the entry of our drugs into the EU market and various other countries," said Mohammad Mujahidul Islam, executive director (marketing and sales) of Eskayef.

Eskayef is currently exporting products to over 60 countries.

1720827781526.png


"Thanks to modern technologies, facilities, and unwavering dedication, Eskayef Oncology is committed to delivering affordable and globally standard anti-cancer products to patients both at home and abroad," he said.

Prof Golam Mohiuddin Faruque, president of the Bangladesh Cancer Society, said Bangladesh has achieved tremendous improvement in cancer treatment and anti-cancer drug manufacturing.

Bangladesh exported cancer drugs worth Tk 1,000 crore in 2023. The amount was around Tk 500 crore in 2019. Local sales of cancer drugs have reached Tk 800 crore to Tk 1,000 crore as demand is increasing by an average of 15 percent each year, according to the manufacturers.

Prof SM Abdur Rahman, chairman of the pharmacy department at the University of Dhaka, said Bangladesh's pharmaceutical companies have set up world-class manufacturing plants equipped with sophisticated machinery, enabling them to produce top-class drugs.

He thinks there is no doubt that Bangladesh's oncology products will dominate the world market, meeting global standards, quality, and cost-effectiveness.

There are areas of concern.

After 2026, when Bangladesh graduates from the group of least-developed countries, local pharmaceutical companies will have to follow patent guidelines while manufacturing drugs, including oncology products. If medicines are produced following the patent rights, the drugs will be costlier in the local market.

1720827814860.png


To avert the situation, Bangladesh initially tried to extend its Trade-Related Aspects of Intellectual Property Rights (TRIPS) waiver by six to nine years and then up to January 1, 2033. However, at the 12th Ministerial Conference of the World Trade Organisation (WTO) in Geneva in June 2022, global leaders did not extend the TRIPS deadline for graduating LDCs.

Under the current agreement, drug-makers in LDCs can produce any generic medicine without having to follow patent guidelines until January 1, 2033. But the benefit is not applicable to graduating LDCs such as Bangladesh.

Beacon's Alam, however, said it would be applicable for only new molecules, which comprise few drugs. "So, the pharmaceuticals sector will not face significant challenges after graduation."​
 

Renata begins exporting two new medicines to the UK

Renata PLC, a leading pharmaceutical company in Bangladesh, has started exporting two new products to the UK, thereby expanding its product portfolio in the country, according to a company disclosure.

Posted on the Dhaka Stock Exchange (DSE) website, the disclosure informed that Renata shipped its first consignment of Sertraline 100 milligram (mg) and Propylthiouracil 50mg tablets to the UK yesterday.

The listed drug maker also said the two products manufactured at its facility in Gazipur will be marketed in the UK under its own brand.

Sertraline is the most commonly prescribed antidepressant in the UK market, with more than 23 million prescriptions dispensed in 2023.

It is used for certain conditions, including depression, anxiety, obsessive-compulsive disorder and post-traumatic stress disorder.

The second product, Propylthiouracil, is a key treatment for physical ailments such as hyperthyroidism, particularly in patients with Graves' disease.

The disclosure also said the addition of this product reinforces Renata's commitment to providing essential thyroid management solutions as a part of the company's chronic care portfolio in the UK.

Sertraline and Propylthiouracil are marketed in Bangladesh under the brand names Seronex and PTU respectively.​
 

Three drug makers ready to produce raw materials in API park

1729123608638.png


After successful trials, three local drug makers are set to begin full-fledged commercial production of active pharmaceutical ingredients (APIs) at the BSCIC API Industrial Park at Gazaria in Munshiganj.

Two of the factories, ACME Laboratories and Ibn Sina Pharmaceutical, are currently awaiting regulatory approval, while the third, Healthcare Pharmaceuticals, has recently begun limited-scale commercial production of these essential drug-making raw materials.

"We obtained approval from the Directorate General of Drug Administration (DGDA) and began manufacturing on a limited scale recently," said Muhammad Halimuzzaman, managing director of Healthcare Pharmaceuticals.

He said full-scale commercial production of some items requires permission from the narcotics department, which they are currently awaiting.

The Bangladesh Small and Cottage Industries Corporation (BSCIC) established the industrial park along the Dhaka-Chattogram highway, allocating 42 plots for 21 industrial facilities.

Bangladesh now meets over 97 percent of its domestic demand for pharmaceutical products and exports medicine to more than 151 countries worldwide

So far, four local manufacturers -- ACME Laboratories, Healthcare Pharmaceuticals, Ibn Sina Pharmaceutical and UniMed-UniHealth Fine Chemicals -- have set up factories there.

Commercial production at the park spanning 200 acres was scheduled to begin in April of this year. However, it has yet to be connected to the national gas grid or equipped with a functional common effluent treatment plant (ETP).

"We commenced trial production nearly three months ago and submitted samples to the drug directorate for approval," said Mizanur Rahman Sinha, managing director of ACME Laboratories Ltd.

According to Sinha, ACME has already invested Tk 500 crore to import sophisticated machinery from the United States, Germany, Japan and India to ensure local APIs meet global standards.

He said the ACME unit will be able to produce APIs worth Tk 600 crore annually.

Jasim Uddin, chief financial officer of Ibn Sina Pharmaceutical, said they submitted their samples to the drug directorate in June this year.

"If the DGDA approves, we will proceed with commercial production of APIs. Our plant is fully ready to begin commercial production."

However, Nazmul Hossain, director of UniMed UniHealth Pharmaceuticals Ltd, said current market conditions are unfavourable for commencing commercial production due to high financing costs.

"We will begin commercial production once financing costs come down," he added.

Factories ready, park not

The initiative to establish the API park was taken in 2008, while the BSCIC allocated the plots to drug makers in 2018.

While pharmaceutical giants like Square and Beximco Pharmaceuticals got plots there, they are yet to begin factory construction.

Previously, SM Shafiuzzaman, secretary general of the Bangladesh Association of Pharmaceutical Industries, which represents 265 local drug makers, said most of their members have not set up factories at the park due to the long delay in providing gas connections.

Healthcare Pharmaceuticals Managing Director Halimuzzaman said API manufacturing needs uninterrupted electricity supply, necessitating a gas-run captive power plant.

Diesel-fueled electricity is expensive, ultimately pushing up costs.

Besides, he mentioned potential health hazards and pollution risks associated with pharmaceutical raw material manufacturing without a functional ETP.

Ashraf Uddin Ahmed Khan, the current chairman of the BSCIC, said he was unaware of the latest condition of the API park as he had only recently been appointed to the post.

Sanjoy Kumar Bhowmik, the immediate past chairman of the BSCIC, told The Daily Star that Titas Gas Transmission and Distribution Company assured them of gas connections.

'A worthwhile venture'

The country's pharmaceutical industry has undergone a remarkable transformation in recent decades from a heavily import-dependent sector to one that is nearly self-sufficient.

Bangladesh now meets over 97 percent of its domestic demand for pharmaceutical products and exports medicine to more than 151 countries worldwide.

But the country is still reliant on imported raw materials for around 85 percent of its requirements for both biological and non-biological small molecule APIs, incurring costs of around $1.3 billion annually.

These APIs are mainly sourced from China and India.

Local pharmaceutical companies cater to the remaining demand, with at least six companies, including Square Pharmaceuticals and Incepta Pharmaceuticals, producing APIs worth more than Tk 2,000 crore annually.

Industry people say at least 50 percent of the country's demand for APIs could be met through local production if more big companies would invest in the sector.

This means the remaining 50 percent would still need to be imported since it is now possible to manufacture only non-biological small molecule APIs locally.

"Still, it is a worthwhile venture as the domestic market for non-biological small molecule APIs is currently worth around Tk 6,500 crore," said Sinha of ACME Laboratories.​
 

Square Pharma sees rare drop in sales

1731630224819.png

Square Pharma

Sales of Square Pharmaceuticals, the largest drug producer in Bangladesh, dropped slightly to Tk 1,774 crore in the July-September period of the current fiscal, down 0.36 percent year-on-year, amid the recent political changeover.

This is the first time the drugmaker has seen its sales fall since at least 2010, as per data on the company's website. Even during the pandemic, the company did not witness a decline in sales.

Despite the decline in sales, the drugmaker in the quarter managed to post a 1.53 percent profit year-on-year to Tk 609 crore thanks to income from its subsidiaries and investments in several securities.

In the quarter, the income of Square Pharmaceuticals from investments rose by around 35 percent to Tk 146 crore, while its profits from associated companies surged 54 percent to around Tk 57 crore, the financial report showed.

At the same time, its earnings per share stands at Tk 6.87, up from Tk 6.77 previously.

The sales dropped due to multiple factors, including the turmoil centring the July-August movement, internet shutdown, labour unrest and floods in several districts of the country.

Shares of Square Pharmaceuticals rose 0.22 percent to Tk 224.90 at the Dhaka Stock Exchange yesterday.​
 

Pharma exports hit record high in Nov


1734052480493.png


Pharmaceutical exports from Bangladesh notched record growth in November this year as local drug makers secured new markets and larger orders, according to industry people.

Data from the Export Promotion Bureau (EPB) shows that the country's pharmaceutical shipments rose by 52.45 percent year-on-year to $92.58 million in the July-November period of the current fiscal year.

In November alone the sector fetched $22.73 million from exports, indicating substantial growth from the $13.14 million earned during the same month a year prior.

"Export orders usually increase this time each year if the overall situation remains normal, as reflected by the shipment volume," said Monjurul Alam, chief executive officer of Beacon Medicare Limited, a concern of Beacon Pharmaceuticals.

While acknowledging that export orders have risen significantly, he said the growth was aided by gradual improvements in the country's US dollar stock and the subsequent easing of letters of credit (LCs) opening for raw material imports.

And although the local pharmaceutical industry was rocked by worker unrest in September, the situation has been stabilising since October.

"Drug makers are now keen on boosting exports and finding new destinations," Alam added while citing how the international marketing teams of local exporters are working hard to this end.

Mujahidul Islam, executive director (marketing and sales) for both domestic and international markets at Eskayef Pharmaceuticals Limited, said major importers like Sri Lanka, Nepal and Myanmar have resumed placing orders.

Against this backdrop, he expressed optimism that exports will grow further in the coming days as global economies continue to recover from economic crises brought on by the Russia-Ukraine war.

Besides, existing importers have started placing larger orders, Islam said while adding that the export growth was not equally shared by all in the local industry.

Ananta Saha, international business manager of Renata Limited, said they achieved their desired export growth this year despite facing a number of challenges, such as rising raw material import prices.

"Although we did not get significant growth over the past five months, the current growth rate is sustainable," he added.

Saha also said nearly all of the leading pharmaceutical exporters are working to secure approval from drug enforcement agencies of foreign economies in a bid to expand their global footprints.

However, he informed that despite increased exports, the profit margins of local drug makers decreased as a result of the higher US dollar rates and rising raw material import costs.

"Manufacturers could not raise their product prices even though taka's depreciation against the greenback hiked the production cost," Saha added.

The country exports pharmaceutical products to at least 151 countries, including those in the EU, Africa and Latin America as well as the US, after catering to 98 percent of the domestic demand, according to Bangladesh Association of Pharmaceutical Industries.​
 

Pakistan wants to import medicine from Bangladesh
United News of Bangladesh . Dhaka 15 December, 2024, 17:24

1734308317288.png

Pakistan high commissioner to Bangladesh Syed Ahmed Maroof calls on health adviser Nurjahan Begum at her office in Dhaka on Sunday. | UNB Photo

Pakistan has shown its keenness to import medicine from Bangladesh.

Pakistan high commissioner to Bangladesh Syed Ahmed Maroof expressed the interest when he called on health adviser Nurjahan Begum at her office on Sunday.

Bangladesh had made significant progress in the pharmaceutical sector, and Pakistan was interested in importing medicines from Bangladesh, said Maroof.

Healthcare, trade, and overall cooperation between the two countries came for discussion during the meeting.​
 

Latest Tweets

ThunderCat Bilal9 ThunderCat wrote on Bilal9's profile.
Seeing you're the more like-minded Bangladeshis, I was going advocate having you as moderator. Good to know it's already been done.
ThunderCat Egyptian ThunderCat wrote on Egyptian's profile.
Have you considered adding a cool Egyptian symbol as your avatar?
ThunderCat Lulldapull ThunderCat wrote on Lulldapull's profile.

Latest Posts

Back